Tretizen 20 (Isotretinoin) is a preparation of anti-inflammatory and anti-acne type, belonging to the class of retinoids. In its action is similar to vitamin A.
Form of issue and composition
The drug is available in the form of tablets containing orange-yellowish powder in a dosage of 2.5, 5, 10 and 20 mg. The active substance is isotretinoin.
Dosage and route of administration
Tablets are taken orally for 3-4 months. The daily dosage is from 0.1 to 1 mg per kilogram of body weight. If the patient tolerates the drug well, the dose can be increased to 2 mg per kilogram of the body after 10-15 days of therapy.
Tretizen 20: Indications for use
The main indications for the use of the drug are the following:
• a complicated degree of nodular-cystic acne, with spread on the face and body;
• Complicated form of recurrent acne;
• recurrent rash with a passing seborrheic manifestation;
• Acne of pink type;
• Perioral dermatitis;
Contraindications for use
Among the main contraindications are:
• Vitamin A hyperavitaminosis;
• period of pregnancy;
• the period of breastfeeding;
• simultaneous use of tetracycline group preparations;
• severe type of hyperlipidemia;
• severe renal failure.
Side effects of Tretizen 20
If the dosage is incorrectly prescribed and if there are contraindications, the following side effects may appear in the patient:
• severe sweating and itching of the skin;
• headache and dizziness;
Anemia and severe weakness;
• decrease in the acuity of night vision;
Nausea and constipation.
If side effects occur, first try to reduce the dosage, which at the time of treatment can be much higher than it really is.
Tretizen 20 overdose
In case of drug overdose, the usual side effects may occur with a background of severe vomiting and diarrhea. When taking too large a dose, it is necessary to rinse the stomach and take an antihistamine.
Pregnancy and lactation
During pregnancy, the drug is not allowed to use in any of the trimesters. This same rule also applies during breastfeeding. Before planning a baby, taking Isotretinoin should be stopped 8 weeks before the start of the process. If this rule is ignored, the fetus may develop intrauterine pathologies that are life-threatening. During lactation, the active substance is secreted into breast milk, which can also contribute to the development of side effects in the newborn.
The use of Isotretinoin in precise dosages and without pronounced contraindications ensures that you will quickly get rid of acne manifestations and return to a full life without embarrassment and fear for your appearance.
What is isotretinoin?
In its pure form, isotretinoin is a powder of a bright orange or slightly yellowish hue without a pronounced smell. This substance belongs to the class of active biological form of vitamin A, responsible for the tone and condition of the skin, as well as the work of all skin secretions.
The substance does not enter into direct reactions with the nuclear receptors of retinoic acid. In this case, isotretinoin rapidly changes its properties and becomes tretinoin. Thanks to such processes, buying isotretinoin, there are disruptions in the work of dangerous genes that cause protein resolution.
At the same time, there is a decrease in the secretion of sebaceous glands, which helps to get rid of the manifestations of acne. Notable results from the use of retinoids are visible already in the middle of the course of treatment.
The effect of Tretizen 20 on the skin and body
After entering the body, an instantaneous reaction of isotretinoin into the form of tretinoin takes place, which in turn triggers the following processes:
• removal of inflammatory processes caused by clogging of pores and excessive sebaceous glands;
• Establishment of sebum production;
• elimination of traces and manifestation of seborrhea;
• decrease in the number of bacteria that cause and provoke acne;
• stimulation of renewal of epidermal cells;
• additionally keratolytic effect occurs.
It should be noted that isotretinoin refers to the retinoids of the natural and physiological class, which causes its rapid and easy absorption by the skin cells.
Form of issue and their differences
Tretizen 20 is available in the form of tablets and gel. Medicinal products do not have significant differences in the effect on the body, but differ in the duration of the course and ease of use.
Tablets are taken orally in a strictly prescribed dosage for 2-3 months. At the same time, it is worthwhile to understand that in order to consolidate the result, repeated therapy is mandatory, which consolidates and enhances the success of treatment.
The gel not only eliminates inflammation, but also helps moisturize and nourish the skin. Apply to clean and dry skin the recommended number of times within 1-2 months.
If you are still thinking about whether to buy isotretinoin, drop all doubts aside. After all, the beauty and health of the skin can be obtained without complex and expensive services, the result of which is observed only the first time.
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