View Cart “T3-Max-25” has been added to your cart.
Maxi-Fen-20 on dopingteam.com

Maxi-Fen-20

$53.90

Manufacturer: Maxtreme
Substance: Tamoxifen (Tamoxifen Citrate)
Package: 20mg (100 pills)

Pharmachologic effect

Maxi-Fen-20 (Tamoxifen) is a non-steroidal antiestrogenic agent that also has weak estrogenic properties. Its action is based on the ability to block estrogen receptors. Tamoxifen, as well as some of its metabolites, compete with estradiol for binding sites to the cytoplasmic estrogen receptors in the tissues of the mammary gland, uterus, vagina, anterior pituitary gland and tumors with a high estrogen receptor content. In contrast to the receptor complex of estrogen, the receptor complex of tamoxifen does not stimulate the synthesis of DNA in the nucleus, but inhibits cell division, which leads to regression of tumor cells and their death.

Pharmacokinetics

After oral administration, tamoxifen is absorbed well. Cmax in the serum is achieved within the range of 4 to 7 hours after administration of a single dose. Css of tamoxifen in the blood serum is usually achieved after 3-4 weeks of administration.

Metabolized in the liver with the formation of several metabolites. Removal of Maxi-Fen-20 from the body has a two-phase character with an initial T1 / 2 of 7 to 14 hours and followed by a slow terminal T1 / 2 for 7 days. It is allocated mainly in the form of conjugates, mainly with fecal masses and only small amounts are excreted in the urine.

Indications for use of Maxi-Fen-20

  • estrogen-dependent breast cancer in women (especially menopause) and mammary glands in men.

The drug can be used for the treatment of ovarian cancer, endometrial cancer, kidney cancer, melanoma, soft tissue sarcoma in the presence of estrogen receptors in the tumor, as well as for the treatment of prostate cancer in resistance to other drugs.

Dosing regimen

The dosage regimen is usually set individually, depending on the indications. The daily dose is 20-40 mg. As a standard dose, taking 20 mg of tamoxifen inside daily for a long time is recommended. When there are signs of progression of the disease, taking the drug is canceled.

Tablets should be taken without chewing, squeezed with a small amount of liquid, in 1 morning or, dividing the required dose into 2 doses, in the morning and in the evening.

Side effect of Maxi-Fen-20

In the treatment of tamoxifen, the most frequent adverse reactions associated with its anti-estrogenic effect, manifested in the form of paroxysmal sensations of heat (tides), vaginal bleeding or discharge, itching in the genital area, alopecia, pain in the area of the lesion, ossalgia, weight gain. Less frequently or rarely, the following adverse reactions were observed: fluid retention, anorexia, nausea, vomiting, constipation, fatigue, depression, confusion, headache, dizziness, drowsiness, fever, skin rash, visual impairment, including corneal changes, cataracts , retinopathy and retrobulbar neuritis.

At the beginning of treatment, local exacerbation of the disease is possible – an increase in the size of soft tissue formations, sometimes accompanied by a pronounced erythema of the affected areas and adjacent areas – which usually occurs within 2 weeks.

The likelihood of thrombophlebitis and thromboembolism may increase.

Sometimes transient leukopenia and thrombocytopenia can occur, as well as an increase in the level of hepatic enzymes, very rarely accompanied by more severe impairment of liver function, such as fatty liver infiltration, cholestasis and hepatitis.

In some patients with bone metastases, gipekalcia was observed at the beginning of the treatment.

Maxi-Fen-20 causes amenorrhea or irregularity of menstrual periods in premenopausal women, as well as reversible development of ovarian cystic tumors.

With long-term treatment with tamoxifen, changes in the endometrium, including hyperplasia, polyps, and in some cases – endometrial cancer, as well as the development of uterine fibroids, can be observed.

Contraindications to the use of Maxi-Fen-20

  • pregnancy and lactation;
  • increased sensitivity to tamoxifen and / or any other ingredient in the drug.

With caution – renal failure, diabetes, eye diseases (including cataracts), deep vein thrombosis and thromboembolic disease (including in the history), hyperlipidemia, leukopenia, thrombocytopenia, hypercalcemia.

Use of Maxi-Fen-20 in pregnancy and lactation

Contraindication: pregnancy and lactation.

Application for violations of kidney function

With caution – kidney failure.

Impact on the ability to drive vehicles and manage mechanisms

During the treatment period, it is necessary to refrain from engaging in potentially dangerous activities that require a high concentration of attention and speed of psychomotor reactions.

Overdose Maxi-Fen-20

Acute overdose of tamoxifen in humans was not observed. It should be expected that an overdose can cause an increase in the above-described adverse reactions.

Specific antidotes do not exist, treatment should be symptomatic.

Drug Interactions

With the simultaneous administration of tamoxifen and cytostatics, the risk of thrombosis increases.

Antacids, H2-histamine receptor blockers and other drugs of similar effect, increasing the pH value in the stomach, can cause premature dissolution and loss of protective effect of the enteric-soluble tablet. The interval between taking tamoxifen and these drugs should be 1-2 hours.

There are reports of increased tamoxifen anticoagulant effect of coumarin drugs (eg, warfarin).

Drugs that reduce the excretion of calcium (eg, thiazide diuretics) may increase the risk of hypercalcemia.

The combined use of tamoxifen and tegafur can promote the development of active chronic hepatitis to cirrhosis of the liver.

The simultaneous use of tamoxifen with other hormonal drugs (especially estrogen-containing contraceptives) leads to a weakening of the specific effects of both drugs.

Conditions of leave from pharmacies

The drug is released by prescription.

クエン酸タモキシフェン 20mg/ml 通販

Additional Information

Manufacturer

Maxtreme

Substance

Tamoxifen (Tamoxifen Citrate)

Package

20mg (100 pills)

Reviews

  1. :

    I gotta say, I’ve never had a bad experience with Dopingteam. Every order has been smooth sailing. And when you’re dealing with stuff like this, that’s exactly what you want. You don’t wanna be stressing about whether or not your gear is gonna show up or if it’s gonna be legit.
  2. :

    I took one Maxi Fen tablet daily, and to my pleasant surprise, I didn’t experience any adverse effects. Maxi Fen proved to be a safe and effective supplement, and I was impressed by its performance.
  3. :

    I hit it lucky when I couldn’t find a decent quality clomid anymore, and then I took a chance with nolva for my PCT. Managed to stopped the sides in its tracks within days! Super good quality, this maxtreme nolva stuff. Wish they made clomid, but whatever, as an anti-estrogen this stuff worked for me 🙂
  4. :

    I don’t mess around anymore when it comes to my cycles and avoiding serious side effects. I used to only run Nolva as part of my PCT but now I just run lower doses of it on every cycle so it never gets to the point where it’s being reactive instead of preventative. I do notice that when I use it during my cycle I get a little bit of the brain fog I’ve heard other people describe, but it’s not too bad. It makes my skin look amazing too, which is great since usually it looks terrible. Well worth using it during cycle if you ask me.
  5. :

    I’ve never had any issues with my recovery, maybe because I had never used anything more than test and primo, but I decided I wanted something a little stronger this time around, I added in some EQ and Dbol instead of primo… Then the issues happened, I started to get some sensitivity around the nipples and panicked… Luckily the experts over at dopingteam were able to sort me out in no time! Told me to take some of this nolva and it should sort the issue for me! It worked a treat, after about a week the tenderness went away, and it didn’t come back again after that, THANK GOD
  6. :

    This maxtreme nolva has been a great game changer for my PCT since I’ve started using it. I have noticed a much better increase in the gains I’ve been able to keep, as well as the general feeling I have during the time I’m on my PCT. It used to be something that I really wasn’t looking forward to and now it’s a simple normal part of my cycle that I don’t mind at all. If you want to have an easy PCT this is the way to go.
  7. :

    Never used Nolva until recently, honestly, I didn’t see the point. I never had any issues so I thought it would just be a waste of money! That was until I got my bloods done and saw my levels were all out of whack! I had to come off the sauce and get myself sorted so I ordered some of this, HCG, and Clomid and ran a pretty extensive PCT/Recovery phase! The stuff worked a treat and I will definitely be smarter about my PED use in the future
  8. :

    Maxtreme is probably the best out there, Maxi-fen is of incredible quality. Every cycle I do I will only use maxtreme products. I have used many other brands in the past but none can even come close to this company
  9. :

    In my opinion, if you suffer from estrogen sensitivity, forget the AIs, get some of this nolva and a low dose of Masteron and you’ll get much better results! Works a dream, doesn’t crash your estro levels and helps build more muscle! Why not right!?

Add a review

Please login to post questions