Maxi-Fen-10 on



Manufacturer: Maxtreme
Substance: Tamoxifen (Tamoxifen Citrate)
Package: 10mg (50 pills )

The drug Maxi-Fen-10 (Tamoxifen) belongs to the group of antiestrogenic agents with pronounced antitumor effect.

Form of formulation and composition of the preparation

The drug Maxi-Fen-10 is available in the form of tablets for oral administration. The tablets are coated with a white or yellowish film coating and packed in 10 pieces in contour squares in a cardboard bundle with the attached detailed instructions. Each pill contains active active substance Tamoxifen in the amount of 10 mg, 20 mg, 30 mg, 40 mg. In addition, the preparation includes a number of auxiliary substances – lactose monohydrate, povidone, microcrystalline cellulose.

Indications for use

Tablets Maxi-Fen-10is prescribed to patients for the treatment of the following pathologies:

  • breast cancer in women, associated with the amount of estrogen in the body;
  • breast cancer in men, developed after castration;
  • ovarian cancer;
  • endometrial cancer of the uterus;
  • kidney cancer;
  • sarcoma of soft tissues in the presence of estrogen receptors in the tumor;
  • prostate cancer in men with no therapeutic effect on other drugs.

Contraindications Maxi-Fen-10

Before starting the use of the drug, it is necessary to carefully study the accompanying instructions, since the tablets have a number of contraindications:

  • pregnancy or suspected of it;
  • the period of breastfeeding;
  • individual hypersensitivity to the components of the drug.

Relative contraindications to the use of the drug are:

  • kidney failure;
  • cataract;
  • increased intraocular pressure;
  • leukopenia;
  • thrombocytopenia;
  • hypercalcemia;
  • diabetes;
  • thrombosis;
  • simultaneous treatment with anticoagulants of indirect action.

Method of administration and dosage Maxi-Fen-10

The dose of the drug and the duration of the course of therapy is determined individually for each individual patient, which depends on the diagnosis, the severity of the clinical picture of the disease, the presence of complications.

At the initial stage of treatment appoint 20 mg of drug per day, gradually if necessary increasing the dose. Tablets are taken orally, without chewing or grinding, with a small amount of liquid.

If the symptoms do not decrease, but progress and the patient feels worse, taking pills Tamoxifen immediately stop and go to the doctor.

Use of the drug during pregnancy and during breastfeeding

Clinical experience of the use of tablets Tamoxifen among pregnant women is not available, therefore, it is not recommended to prescribe the drug to future mothers. It is not known how therapy can affect the intrauterine development of the baby. If you suspect a pregnancy while taking the medication, the therapy should be stopped immediately and consult a doctor.

Active active substance of the drug is excreted in breast milk and may adversely affect the baby who is breastfed. Given this information, the drug tablets should not be given to nursing mothers, and if necessary, therapy should decide whether to stop lactation.

Adverse Events

With the use of the drug Tamoxifen, side effects are associated with the antiestrogenic effect of tablets and are manifested as:

  • bleeding from the genital tract by the type of menstruation;
  • sensation of heat in the head and face by the type of tides;
  • itching of the genitals and increased vaginal discharge;
  • baldness;
  • weight gain;
  • fluid retention in the body, swelling of the limbs and face;
  • anorexia, nausea, vomiting, stool disorders, bloating;
  • increased fatigue, complaints of chills, apathy, drowsiness;
  • rash on the skin, hives ;
  • cataract, retinopathy, neuritis;
  • headaches and dizziness ;
  • leukopenia and thrombocytopenia;
  • hepatitis, jaundice development severe liver damage;
  • development of cysts on the surface of the ovaries.

The use of tablets Tamoxifen in women often causes a delay in menstruation, amenorrhea , changes in the endometrium, tissue hyperplasia, uterine fibroids, and in rare cases the development of endometrial cancer.

An overdose of the Maxi-Fen-10

Cases of drug overdose have not been described, however, to avoid the increase of the above described adverse reactions, it is not recommended to exceed the dose prescribed by the doctor. There are no antidotes of the drug, in case of signs of overdose, the patient is vomited, washed stomach and perform symptomatic treatment.

Interaction of the Maxi-Fen-10 with other drugs

The drug Maxi-Fen-10 is not recommended to be prescribed to patients simultaneously with cytostatics, as this increases the risk of thrombosis and changes in the clinical picture of the blood.

The drug should not be combined with antacids, blockers of histamine H2 receptors, as this can provoke premature dissolution of the enteric-dissolving tablet coating and the development of side effects.

Against the background of the use of Tamoxifen, the therapeutic effect of anticoagulants of indirect action may be increased, which should be taken into account in this drug interaction.

The simultaneous use of a thiazide series with diuretics may increase the risk of hypercalcaemia and side effects from the kidneys.

The drug Tamoxifen is not recommended to be administered to patients simultaneously with Tegafur, since this drug interaction leads to the development of chronic hepatitis and cirrhosis of the liver.

With the simultaneous administration of tamoxifen tablets with other hormonal drugs, for example, estrogen-containing contraceptives, the therapeutic effect of both drugs may be weakened.

During treatment with the drug, patients need to regularly monitor the blood picture, blood pressure, pulse and other important parameters.

Tamoxifen is able to cause dizziness and drowsiness, so during treatment with the drug should refrain from driving and complex mechanisms that require increased concentration.

Analogues of Maxi-Fen-10

Analogues of the drug Maxi-Fen-10 are:

  • Zitazonium tablets;
  • Tamoxifen Hexal;
  • Tamoxifen Ebwe;
  • VERO-Tamoxifen.

All listed drugs have limitations and contraindications, so before replacing the prescribed remedy should always consult with your doctor.

Leave and storage conditions

Tablets Maxi-Fen-10 are dispensed from pharmacies on prescription. Keep the tablets out of the reach of children in a dark, cool place. Shelf life of the drug is 4 years from the date of manufacture, at the end of this period the drug can not be used for treatment.


クエン酸タモキシフェン 10mg/ml 通販

Additional Information




Tamoxifen (Tamoxifen Citrate)


10mg (50 pills)


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