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Kamagra 100 on dopingteam.com

Kamagra 100

$17.60

Manufacturer: Indian Brand
Substance: Sildenafil
Package: 100mg (12 pills)

Composition Kamagra 100

active ingredient:  sildenafil;

1 tablet contains sildenafil citrate in terms of sildenafil 50 mg or 100 mg

Auxiliary substances:  microcrystalline cellulose, magnesium stearate, sodium starch (type A), povidone, talc, hypromellose, coating Instacoat Sol IC-S-3788 (green) *, titanium dioxide (E 171)

* Instacoat Sol IC-S-3788 (green):   talcum, hypromellose, polyethylene glycol, titanium dioxide

(E 171), quinoline yellow (E 104), brilliant blue (E 133).

Dosage form

The tablets covered with a cover.

Basic physical and chemical properties:

diamond coated tablets, green, embossed “ar” on one side and “KGR 50” on the other;

diamond coated tablets, green, embossed “ar” on one side and “KGR 100” on the other.

Pharmacological group

Means used for erectile dysfunction. Sildenafil. ATX Code G04B E03.

Pharmacological properties

Pharmacodynamics .

Kamagra 100 is a drug for oral administration, intended for the treatment of erectile dysfunction. With sexual stimulation, the drug restores reduced erectile function by increasing the flow of blood to the penis.

A physiological mechanism that leads to an erection, including the release of nitric oxide (NO) in cavernous bodies during sexual arousal. The released nitric oxide activates the enzyme guanylate cyclase, which stimulates the increase in the level of cyclic guanosine monophosphate (cGMP), which, in turn, causes relaxation of the smooth muscles of the cavernous bodies, contributing to the influx of blood.

Kamagra 100 Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase

5 (PDE-5) in cavernous bodies, where PDE-5 is responsible for the decay of cGMP. Effects of sildenafil on erection are peripheral. Sildenafil does not have a direct relaxing effect on isolated cavernous bodies of a person, but powerfully enhances the relaxing effect of NO on this tissue. When the metabolic pathway of NO / cGMP is activated, which occurs during sexual stimulation, sildenafil inhibition of PDE5 leads to an increase in the level of cGMP in cavernous bodies. Thus, in order for sildenafil to cause a necessary pharmacological effect, sexual arousal is necessary.

Studies  in vitro  have shown selective effects of sildenafil on PDE-5, which is actively involved in the process of erection. The effect of sildenafil on PDE-5 is more powerful than other known phosphodiesterases. This effect is 10 times more powerful than the effect on PDE6, involved in the processes of phototransformation in the retina. When the maximum recommended doses are used, the selectivity of sildenafil in PDE-5 is 80 times greater than its selectivity to PDE1, in

700 times higher than in FDE2, FDEZ, FDE4, FDE7, FDE8, FDE9, PDE10 and FDE11. In particular, the selectivity of sildenafil in PDE-5 is 4000 times greater than its selectivity to FDEZ-cGMP-specific isoform PDE, involved in the regulation of cardiac contractility.

Pharmacokinetics.

Absorption.  Kamagra 100 (Sildenafil) is rapidly absorbed. The maximum plasma concentrations of the drug is achieved within 30-120 minutes (with a median of 60 min) after its oral application on an empty stomach. Average bioavailability after oral administration is 41% (with a range of values from 25% to 63%). In the recommended dose range (from 25 to 100 mg), the area under the concentration-time curve (AUC) and the maximum concentration (  max  ) of sildenafil after its oral administration increase in proportion to the dose.

When Kamagra 100 is used during food intake, the degree of absorption decreases with an average elongation of T  max  to 60 minutes and an average decrease of C  max  by 29%.

Distribution.  The average equilibrium volume of distribution (V  d  ) is 105 liters, which indicates the distribution of the drug in the tissues of the body. After a single oral intake of sildenafil at a dose of 100 mg, the average maximum total plasma concentration of sildenafil is approximately 440 ng / ml (the coefficient of variation is 40%). Since binding of sildenafil and its main N-desmethyl metabolite to plasma proteins is 96%, the average maximum plasma concentration of free sildenafil reaches 18 ng / ml (38 nmol). The degree of binding to plasma proteins does not depend on the total concentrations of sildenafil.

In healthy volunteers taking sildenafil once in a dose of 100 mg, after 90 minutes, less than 0.0002% (an average of 188 ng) of the dose was determined in the ejaculate.

Indications

The drug is recommended for men with erectile dysfunction, which is defined as the inability to achieve or support an erection of the penis necessary for a successful sexual intercourse.

For effective action of the drug, sexual arousal is necessary.

Contraindications Kamagra 100

  • Hypersensitivity to the active substance or to any of the excipients of the drug.
  • Simultaneous use of nitric oxide (such as amyl nitrite) or nitrates in any form with donors is contraindicated, since it is known that sildenafil affects the pathways of nitric oxide / cyclic guanosine monophosphate (cGMP) metabolism and potentiates the hypotensive effect of nitrates.
  • Conditions in which sexual activity is not recommended (for example, severe cardiovascular disorders, such as unstable angina or severe heart failure).
  • Loss of vision of one eye due to non-arterial anterior ischemic neuropathy of the optic nerve, regardless of whether this pathology is associated with previous use of PDE-5 inhibitors or not.
  • The presence of such diseases as severe liver dysfunction, arterial hypotension (arterial pressure below 90/50 mm Pg.t.), recent stroke or myocardial infarction and known hereditary degenerative diseases of the retina, such as retinitis pigmentosa (a small number of such patients has genetic disorders of PDE of the retina), since the safety of sildenafil has not been studied in such subgroups of patients.

Overdose Kamagra 100

Using a single dose of sildenafil up to 800 mg, adverse reactions were similar to those observed with sildenafil at lower doses, but were more frequent and more severe. The use of sildenafil in a dose of 200 mg resulted in increased efficacy, but caused an increase in the incidence of adverse reactions (headache, hot flashes, dizziness, dyspepsia, nasal congestion, visual impairment).

In case of an overdose, if necessary, regular supportive measures should be taken. Acceleration of the clearance of sildenafil during hemodialysis is unlikely due to the high degree of binding of the drug to plasma proteins and the absence of elimination of sildenafil with urine.

Adverse Reactions

The most common reported adverse reactions such as headache, flushing, indigestion, nasal congestion, back pain, dizziness, nausea, hot flashes, blurred vision, cyanopsy and blurred vision.

Infections and infestations:  rhinitis.

From the immune system:  hypersensitivity reactions, including anaphylactic shock, angioedema, fever.

From the side of the nervous system:  headache, dizziness, sleep disturbance, insomnia, drowsiness, tremor, ataxia, neuralgia, neuropathy, paresthesia, hypesthesia, decreased reflexes, sensitization, stroke, syncope, cerebral vascular thrombosis, transient ischemic attack, dysphasia, convulsions , relapses by court, fainting.

From the side of the organ of vision: impairment of color perception (chloropsy, chromatopsy, cyanopsy, erythropsy, xanthopsia), visual disturbances, blurred vision, lacrimation disorders (dry eyes, tearing and tearing), eye pain, photophobia, photopsy, eye hyperemia, brightness of vision, conjunctivitis , non-arterial anterior ischemic optic nerve neuropathy, retinal vascular occlusion, retinal hemorrhage, arteriosclerotic retinopathy, retinal disorders, glaucoma, visual field defects, diplopia, decreased o Trot vision, myopia, asthenopia floating vitreous opacities, disorders of the iris mydriasis, appearance luminous circles around the light source (halo) in the field of view, eye edema, swelling of the eye, disorders of the eye, hyperemia of conjunctiva, ocular irritation,

From the organs of hearing:  vertigo, ringing in the ears, deafness.

From the cardiovascular system:  hot flashes, arterial hypertension, arterial / postural hypotension, palpitations, tachycardia, myocardial ischemia / myocardial infarction, atrial fibrillation, AV blockade, ventricular arrhythmia, angina / unstable angina, sudden cardiac arrest, heart failure.

On the part of the respiratory system:  nasal congestion, nosebleeds, laryngitis, pharyngitis, sinusitis, bronchitis, productive cough, congestion of the paranasal sinuses, a feeling of compression in the throat, swelling of the nasal mucosa, dryness in the nose.

On the part of the digestive tract:  dyspepsia, nausea, vomiting, dry mouth, gingivitis, stomatitis, glossitis, esophagitis, gastritis, gastroenterocolitis, colitis, diarrhea, impaired liver function, hemorrhoidal bleeding, gastroesophageal reflux disease, upper abdominal pain, cavity hypoesthesia cavity.

Shelf life

3 years.

Storage conditions

Store at a temperature of no higher than 30 ° C in the original packaging.

Keep out of the reach of children.

 

クエン酸シルデナフィル 100mg 通販 – Kamagra 100

Additional Information

Manufacturer

Indian Brand

Substance

Sildenafil

Package

100mg (12 pills)

Reviews

  1. :

    Recently I have struggled a bit in the bedroom and have been looking into supplements to help, I stumbled across this and did some research. It is amazing, I take one pill and around an hour after I am fully ready to go! My erections have never been so solid! I love this product so much!
  2. :

    Being a youngster, well in my 30s I feel like I should not need these ed meds even while juicing but when running heavy doses of deca and dht takes over. It seems to be impossible to perform without the help of these tabs! Needless to say I use them quite regularly when running heavy dosages as they help so much and if I dont use them, it can become very depressing within the bedroom (and embarrassing at times). I used to buy kamagra from a guy up state, but they gave me insane headaches and did not provide any fast results, as where when I take these ones from here they seem to be super effective. Takes a while to hit the US from Sg but I do not mind the wait for better quality pills. These have become a must to have while running high progestin based gear!
  3. :

    This Kamagra is amazing, I had been looking something to improve the performance in the bedroom and this stuff does just that! about 40 mins after taking it and you are good to go. The wife absolutely loves it! It is also fantastically priced for the results you get!
  4. :

    Didnt think too much to these at first. Was using them when was heavy on the deca and has issues but they didnt seem to do the job. Tried few other brands too but no luck, in the end I found out it was not the pills but was the situation. Pretty much I wasnt too happy with my last mrs and after reading on the forums, you gotta be feeling the situation to perform well with these. Reason I knowticed was when we broke up and I had another girl over, I took 100mg and jesus crist is was a mad one. Cant belive that you need to feel the horn for them to work. Dont really understand it tbh but after using these kamagras lately, they seem to be the best I have used out off all the different brands. Have ordered more, as now I know they do the job when needed..well when feeling the girl I suppose, they are outstanding to use! Nearly lost faith in them but found out it was my last relationship I lost faith in haha.
  5. :

    If you’re struggling with ED, then I gotta tell you about Kamagra 100’s. Trust me, I’ve tried so many different pills, and none of them come close to the results I’ve gotten with these bad boys. They’re the real deal, and they work like a charm.
  6. :

    I remember about 10 years ago (?) when I first heard about this stuff. I was traveling and it was something I definitely couldn’t get back here in the US. It’s so much cheaper than the brand name stuff that I had to give it a try just to see. Back then everything was in working order when it came to my man-parts. Fast forward ten years and things aren’t so black and white in that department. I was really happy to see this available here online though, and ordered 5 packs as soon as I saw it. It still works great, which is good news because now I need it more than ever. I’m very glad to see my old friend Kamagra!
  7. :

    I am in my late 50s and my girlfriend is about 20 years younger than me, so I needed a bit of help to keep up.. This Kamagra did exactly that! After the first time I used it, both of our minds were blown by how effective it is! If you are an older guy like myself, or just want that extra boost in the bedroom, I can’t recommend this stuff anymore! It is a life changer!!
  8. :

    So i’m not getting any younger, I’m nearly 60 so my performance in the bedroom isn’t what it used to be… But I researched this Kamagra and wow… It is magical! I take it about 45 mins before some time with the wife and it works wonders! The wife has never been more satisfied!!
  9. :

    This stuff is pretty potent. The first time I tried it I took 2 pills because I thought 2 should always be better than one. That was not advisable. I couldn’t finish to save my life. One pill is all you need. After only taking one everything was much better, and I could still last a very long time on it. No need to waste money taking more when less is actually better.
  10. :

    Kamagra is definitely the new king when it comes to ED pills. I know some of the older guys that have been using viagra for years are loyal to it, but when something works this well and is priced way better it makes everyone jump ship from the overpriced stuff out there. Anyone I know that takes ED pills is now using this, so that has to tell you something about it. Until they start making it more expensive I will keep ordering it because it does at least as good of a job as the big names and it’s a fraction of the price.
  11. :

    To all the guys out there… Buy this Kamagra! Trust me, you will be thanking me for it. I have been taking this stuff for a while now and my girl loves it! It is the best time we have ever had!
  12. :

    I was hesitant to try this kamagra as I had a few bad experiences in the past with ED medication, I saw this was pretty cheap so I thought, whats the harm? After all, I was pretty desperate at this point! After a bit of usage I can safely say this stuff is different! It really works, the only issue I get is the ocassional headache.
  13. :

    Outside of the big 2 brands out there I would have to say that Kamagra is the other one that I’ve heard a lot of times from people. I didn’t want to pay a ton for one of the big name brands since I was just curious to see how well ED pills actually worked. I was not disappointed at all. It had me going all night when I would normally be done after about 10 minutes. I don’t even need to try the other brands now because I know how well the Kamagra works and I don’t need to spend a fortune to get it.
  14. :

    I have been with my partner for a while now and honestly I have never been able to keep up with her needs in the bedroom.. A guy at my work told me about this Kamagra and how well it has helped him out! Now I was a little embarrassed at first because I didn’t think a guy my age should need this stuff, however I wanted to keep things going for the girlfriend, so I ordered some, wow it is great! honestly this has given our relationship a whole new lease of life!
  15. :

    Now I have a pretty limited budget, so seeing the price of this Kamagra I was pretty keen to give it a try! I was starting to struggle a bit mentally as me and the partner haven’t been able to ‘connect’ in a while and it was causing us some stress. This stuff has honestly saved my relationship, I am so thankful for the quality of this product!
  16. :

    Kamagra is the best pill I’ve ever used! Who doesn’t like a bit of fun in the bedroom right!? This stuff will make sure you’re always ready to perform! The ladies absolutely love it, I was a little worried about opinions at first, but nobody cares if I’m honest!

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